Dear Colleague

Welcome to the first issue of Dialog Chemistry News. We are very pleased to offer this new resource designed especially for information professionals and knowledge workers in the chemical industry. In addition to bringing you product and content news, search tips and other information specific to the Dialog and Dialog DataStar products, we will offer other items of interest from industry experts and colleagues. Please take special note of the "call for contributors" section. Our goal is to make this newsletter relevant and valuable for you, so please send us your ideas and feedback. We look forward to hearing from you.

Ieva O. Hartwell, Ph.D.
Content Analysis and
Documentation Specialist, Chemistry

Chemical Structure Searching Content Expanded

Dialog is the ideal starting point for your chemical structure searches. Using DialogLink 5, you can search for over 10 million structures in the chemical and drug pipeline files that matter most to your business, including: Beilstein Facts (File 390), Derwent Chemistry Resource (File 355), Pharmaprojects (Files 128/928) and Prous Drug Data Report (File 452).

Click here to download this 6-page quick guide, "Chemical Structure Searching on Dialog".

Make a note of two additional drug pipeline databases now available for chemical structure searching (CSS), bringing the total number of databases CSS-enabled to eight:

• IMS R&D Focus (Files 445,955) — Provides the latest scientific and commercial developments in international pharmaceutical research and development. Images of chemical structures are available for nearly 6,000 Drug Profile records. See the Bluesheet for more information.
• Prous Science Drugs of the Future™ (File 453) — Contains comprehensive drug monographs providing product information on new compounds, including the synthesis and corresponding schemes, pharmacological action, pharmacokinetics and metabolism, toxicity, clinical studies, manufacturers and references. Information on compounds is continuously updated as advances in development status are disclosed worldwide. See the Bluesheet for more information

Dialog at ACS National Meeting in Washington, D.C.

The American Chemical Society Fall 2005 meeting is scheduled for August 28 to September 1 in Washington, D.C. Dialog will be exhibiting at the meeting as part of the Thomson Scientific booth (#401). Make a note to catch the session on Chemical Structure Searching using DialogLink 5 presented by Ron Kaminecki and Bob Stewart on Tuesday, August 30, 10:15 a.m. to 11:00 a.m. at Exposition Presentation Theater, WCC-Hall B&C.

New CSA Files on Dialog

Thirty databases of subject-specific research from CSA (formerly Cambridge Scientific Abstracts) are being added to Dialog. These files include more than six million records focusing on materials science, high tech, engineering, aerospace, computer sciences, life sciences, environmental and aquatic sciences, and social and library sciences. Currently, 18 databases are available including materials science and high tech files such as METADEX® (File 32), Computer and Information Systems Abstracts (File 56), Electronics and Communications Abstracts (File 57), Solid State and Superconductivity Abstracts (File 68) and the mega-file Technology Resource Database (File 23). The remaining databases will be added throughout 2005. The new files are available on a transactional basis, as well as some by subscription only. Contact your account representative for more information on how to access the CSA databases. Review "Dialog Strengthens Sci-Tech Collection With Addition of CSA Databases" in the Chronolog (Issue 3, 2005) for more details.

Pharmaprojects Enhancements

Pharmaprojects on Dialog and Dialog DataStar has been enhanced to include a new protein drug target field. Additionally, Lipinski Parameters and Rotatable Bonds have been assigned to all drug profiles that have chemical structures. These enhancements affect Files 128 and 928 on Dialog and PHAR, PHZZ, PHLP and PHDI on Dialog DataStar. The protein drug target field lets you identify the leading protein target projects currently in development and the target areas in which your competitors are working. The Lipinski Parameter and Rotatable Bonds provide a number of measures that let you predict the likelihood of a compound's success as an oral drug. The measures have been calculated for all drugs that contain chemical structures. No other database contains both protein drug target and Lipinski data.

More Search Help for Dialog DataStar Chem Databases

Dialog DataStar has added Help text with explanations on how to search a particular field for the following chemical databases: CA Search®: Chemical Abstracts® (1987+) (CHEM)/(1967+) (CHZZ) and CA Search® ONTAP (TRCH). Clicking displayed after the Enter search term drop-down box opens a pop-up window with the help text. If "whole document" is selected, all field descriptions appear; if a particular field is selected, a description for that field appears.

Call for Contributors

Participate in knowledge sharing with your colleagues interested in chemistry-related topics. Share your story suggestions with us at support.dialog.com/enewsletters/contribute/.