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Use the MeSH or EMTREE Explode Feature?
TOPIC: In MEDLINE® (File 154) the Explode feature can be used with MeSH descriptors. MeSH descriptors that have narrower terms can be retrieved in a single search statement using the exclamation mark (!) with that descriptor. For example, all occurrences of the term, LYME DISEASE as a descriptor, plus the narrower term ERYTHEMA CHRONICUM MIGRANS and LYME NEUROBORRELIOSIS as descriptors, can be retrieved with SELECT LYME DISEASE! Multiple terms can be exploded in a single search statement (e.g., SELECT GLOMERULONEPHRITIS! AND INTERFERONS!). The (L) operator can be used to link MeSH subheadings to exploded MeSH headings (e.g., SELECT ESOPHAGEAL DISEASES! (L)SURGERY). For more details on the Explode feature in MEDLINE click here.
The Explode feature in EMBASE® (File72) works much the same way with EMTREE descriptors. For details on EMTREE in EMBASE click here.
In this example, you will cast the widest descriptor net in MEDLINE regarding headache disorders.
COMMAND SUMMARY
BEGIN 154
EXPAND HEADACHE DISORDERS
EXPAND E3
SELECT R1 OR R6:R18
SELECT HEADACHE DISORDERS!
DISPLAY SETS
TYPE S1/8/1-3
TYPE S1/9/1
HOW TO...

1. BEGIN File 154 to search MEDLINE.
2. EXPAND the descriptor term or phrase.
You see that there are 17 related terms in the Related Term column. |

?b 154
File 154:MEDLINE(R) 1990-2007/Mar 15
(c) format only 2007 Dialog
Set Items Description
--- ----- -----------
?e headache disorders
Ref Items RT Index-term
E1 24 HEADACHE //POST-TRAUMATIC (POST-TRAUMATIC HEADA
E2 893 HEADACHE //TENSION-TYPE (TENSION-TYPE HEADACHE)
E3 753 17 *HEADACHE DISORDERS
E4 4 HEADACHE DISORDERS --BLOOD --BL
E5 5 HEADACHE DISORDERS --CEREBROSPINAL FLUID --CF
E6 68 HEADACHE DISORDERS --CHEMICALLY INDUCED --CI
E7 107 HEADACHE DISORDERS --CLASSIFICATION --CL
E8 47 HEADACHE DISORDERS --COMPLICATIONS --CO
E9 238 HEADACHE DISORDERS --DIAGNOSIS --DI
E10 181 HEADACHE DISORDERS --DRUG THERAPY --DT
E11 10 HEADACHE DISORDERS --ECONOMICS --EC
E12 136 HEADACHE DISORDERS --EPIDEMIOLOGY --EP
E13 196 HEADACHE DISORDERS --ETIOLOGY --ET
E14 4 HEADACHE DISORDERS --GENETICS --GE
E15 5 HEADACHE DISORDERS --HISTORY --HI
E16 3 HEADACHE DISORDERS --IMMUNOLOGY --IM
E17 11 HEADACHE DISORDERS --METABOLISM --ME
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3. EXPAND the E reference number that shows related terms.
There is a Descriptor code (DC=), narrower terms (N), a related term (R) and cross-reference terms (X).
Note: Alternatively you can EXPAND the descriptor term or phrase within parentheses and save a step.
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?e e3
Ref Items Type RT Index-term
R1 753 17 *HEADACHE DISORDERS
R2 753 X DC=C10.228.140.546. (HEADACHE DISORDERS)
R3 0 X 1 CEPHALGIA SYNDROMES
R4 0 X 1 CHRONIC HEADACHE
R5 27023 R 7 HEADACHE
R6 1087 N 7 CLUSTER HEADACHE
R7 63 N 10 HEADACHE DISORDERS, PRIMARY
R8 37 N 6 HEADACHE DISORDERS, SECONDARY
R9 8484 N 7 MIGRAINE DISORDERS
R10 548 N 7 MIGRAINE WITH AURA
R11 245 N 4 MIGRAINE WITHOUT AURA
R12 19 N 2 PAROXYSMAL HEMICRANIA
R13 40 N 2 POST-DURAL PUNCTURE HEADACHE
R14 24 N 2 POST-TRAUMATIC HEADACHE
R15 18 N 2 SUNCT SYNDROME
R16 893 N 6 TENSION-TYPE HEADACHE
R17 7 N 5 TRIGEMINAL AUTONOMIC CEPHALALGIAS
R18 225 N 7 VASCULAR HEADACHES
?e (headache disorders)
Ref Items Type RT Index-term
R1 753 17 *HEADACHE DISORDERS
R2 753 X DC=C10.228.140.546.(HEADACHE DISORDERS)
R3 0 X 1 CEPHALGIA SYNDROMES
R4 0 X 1 CHRONIC HEADACHE
R5 27023 R 7 HEADACHE
R6 1087 N 7 CLUSTER HEADACHE
R7 63 N 10 HEADACHE DISORDERS, PRIMARY
R8 37 N 6 HEADACHE DISORDERS, SECONDARY
R9 8484 N 7 MIGRAINE DISORDERS
R10 548 N 7 MIGRAINE WITH AURA
R11 245 N 4 MIGRAINE WITHOUT AURA
R12 19 N 2 PAROXYSMAL HEMICRANIA
R13 40 N 2 POST-DURAL PUNCTURE HEADACHE
R14 24 N 2 POST-TRAUMATIC HEADACHE
R15 18 N 2 SUNCT SYNDROME
R16 893 N 6 TENSION-TYPE HEADACHE
R17 7 N 5 TRIGEMINAL AUTONOMIC CEPHALALGIAS
R18 225 N 7 VASCULAR HEADACHES
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4. SELECT the appropriate R number(s).
5. You can also SELECT the explodable term with an exclamation point at the end. Note the results are the same.
Note: The exploded MeSH term picked up all of the narrower terms, as shown here by comparison using the DISPLAY SETS (DS) command. |

?s r1 or r6:r18
753 HEADACHE DISORDERS
10509 CLUSTER HEADACHE:VASCULAR HEADACHES
S2 11027 'HEADACHE DISORDERS' OR R6:R18<
?s headache disorders!
S1 11027 HEADACHE DISORDERS!
?ds
Set Items Description
S1 11027 HEADACHE DISORDERS!
S2 11027 'HEADACHE DISORDERS' OR R6:R18
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6. TYPE a few records in Format 8 to see titles, descriptors and publication years.
Notice that the first record confirms that the Select statement picked up narrower terms.
To select the appropriate record number, look at the range of records in the TYPE command (e.g., 1/8/1-3).
|
?t s1/8/1-3
1/8/1
DIALOG(R)File 154: MEDLINE(R)
(c) format only 2007 Dialog. All rights reserved.
23079952 PMID: 17163262
Tanacetum parthenium and Salix alba (Mig-RL) combination in
migraine prophylaxis: a prospective, open-label study.
2006
Tags: Female; Male
Descriptors: *Migraine Disorders--prevention and control--PC;
*Plant Extracts --therapeutic use--TU; *Salix--chemistry--CH;
*Tanacetum parthenium --chemistry--CH ; Adult;
Capsules--administration and dosage--AD; Drug Administration
Schedule; Drug Combinations; Drugs, Non-Prescription; Humans;
Middle Aged; Migraine Disorders--drug therapy--DT; Migraine
Disorders--pathology--PA; Plant Extracts--administration and
dosage--AD; Plant Extracts --pharmacology--PD; Prospective
Studies; Quality of Life--psychology--PX; Randomized
Controlled Trials; Time Factors; Treatment Outcome
CAS Registry No.: 0 (Capsules); 0 (Drug Combinations); 0
(Drugs, Non-Prescription); 0 (Plant Extracts)
1/8/2
DIALOG(R)File 154: MEDLINE(R)
(c) format only 2007 Dialog. All rights reserved.
23074460 PMID: 17309987
Expanding the differential diagnosis of chronic dizziness.
Feb 2007
Tags: Female; Male
Descriptors: *Anxiety Disorders--diagnosis--DI;
*Dizziness--diagnosis--DI; *Migraine Disorders--diagnosis--DI;
*Post-Concussion Syndrome--diagnosis--DI ; Adolescent; Adult;
Aged; Aged, 80 and over; Autonomic Nervous System
Diseases--diagnosis--DI; Chronic Disease; Diagnosis,
Differential; Diagnostic Techniques, Otological; Humans;
Middle Aged
1/8/3
DIALOG(R)File 154: MEDLINE(R)
(c) format only 2007 Dialog. All rights reserved.
23072910 PMID: 17143907
Patent foramen ovale and migraine.
Jan 2007
Descriptors: *Heart Catheterization--methods--MT; *Heart
Septal Defects, Atrial --complications--CO; *Heart Septal
Defects, Atrial--therapy--TH; *Migraine Disorders--
etiology--ET; *Migraine Disorders--prevention and
control--PC ; Heart Septal Defects, Atrial--epidemiology--EP;
Heart Septal Defects, Atrial--physiopathology--PP; Humans;
Migraine Disorders--epidemiology--EP; Migraine
Disorders--physiopathology--PP; Migraine with
Aura--epidemiology --EP; Migraine with Aura--etiology--ET;
Migraine with Aura --physiopathology--PP; Migraine with
Aura--prevention and control--PC; Prevalence |

7. TYPE a record(s) you wish to view using Format 9 for the complete record.
The citation chosen is record 1.
Note: Part of the record is omitted from this display.
|
?t s1/9/1
1/9/1
DIALOG(R)File 154: MEDLINE(R)
(c) format only 2007 Dialog. All rights reserved.
23079952 PMID: 17163262
Tanacetum parthenium and Salix alba (Mig-RL) combination in
migraine prophylaxis: a prospective, open-label study.
Shrivastava R; Pechadre J C; John G W
Naturveda - Vitro-Bio Research Institute, ZAC de Lavaur,
Issoire, France.
Clinical drug investigation ( New Zealand ) 2006, 26 (5)
p287-96, ISSN: 1173-2563--Print Journal Code: 9504817
Publishing Model Print
Document type: Clinical Trial; Journal Article; Meta-Analysis;
Research Support, Non-U.S. Gov't
Languages: ENGLISH
Main Citation Owner: NLM
Record type: MEDLINE; Completed
Subfile: INDEX MEDICUS
BACKGROUND: Tanacetum parthenium (feverfew) has been used
traditionally to treat migraine, and although its mechanism
of action is not fully understood, serotonin 5-HT receptor
blocking effects have been suggested. T. parthenium and
Salix alba (white willow) either alone or in combination
(Mig-RL) were recently shown to inhibit binding to 5-HT(2A/2C)
receptors; T. parthenium failed to recognise 5-HT(1D)
receptors, whereas S. alba or the combination did. It was
hypothesised that S. alba in combination with T. parthenium
may provide superior migraine prophylactic activity compared
with T. parthenium alone. METHODS: A prospective, open-label
study was performed in 12 patients diagnosed with migraine
without aura. Twelve weeks' treatment with T. parthenium 300
mg plus S. alba 300 mg (Mig-RL) twice daily was administered
to determine the effects of therapy on migraine attack
frequency (primary efficacy criterion), intensity and
duration (secondary efficacy criteria), and quality of life,
together with tolerability for patients. RESULTS: Attack
frequency was reduced by 57.2% at 6 weeks (p < 0.029) and by
61.7% at 12 weeks (p < 0.025) in nine of ten patients, with
70% patients having a reduction of at ….
Tags: Female; Male
Descriptors: *Migraine Disorders--prevention and
control--PC; *Plant Extracts --therapeutic use--TU;
*Salix--chemistry--CH; *Tanacetum parthenium --chemistry--CH
; Adult; Capsules--administration and dosage--AD; Drug
Administration Schedule; Drug Combinations; Drugs,
Non-Prescription; Humans; Middle Aged; Migraine
Disorders--drug therapy--DT; Migraine Disorders--pathology--PA;
Plant Extracts--administration and dosage--AD; Plant Extracts
--pharmacology--PD; Prospective Studies; Quality of
Life--psychology--PX; Randomized Controlled Trials;
Time Factors; Treatment Outcome
CAS Registry No.: 0 (Capsules); 0 (Drug Combinations);
0 (Drugs, Non-Prescription); 0 (Plant Extracts)
Record Date Created: 20061213
Record Date Completed: 20070316 |
RELATED HOW DO I...? SOLUTIONS
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