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The Drug Profile Record

Sharon wanted both a profile of vatalanib and some news on the drug. Let's look first at the Drug Profile Record.

Because the data contained in these profile records is so comprehensive, we'll divide the record into segments so we can discuss each part. I always like to look first at what is called the bibliographic part of the record. This includes the drug name, trade name, company name and drug information.

Tip 2-3

Note: In order to give you supplemental information (tips, learn more comments) about the Dialog record, we have had to add spaces between some of the fields. Print out the complete record for File 445 to have a concise duplicate of the Dialog record you will retrieve online. You can compare it to the parts of the record we will highlight later in the lesson.

Here are a few things Sharon might be interested in from the bibliographic part of this record. She certainly will want to look at the extensive market data in this file.

  1. The basic information section lists the drug name and any brand or trade names for the product. It is important to note that each database may have different product names; thus, omitting consultation of IMS R&D Focus could lead to incomplete bibliographies.

    Each file includes nomenclature not found elsewhere. For effective follow-up searches in biomedical literature files, preliminary compilation of as many applicable alternative names as possible is essential.
  2. IMS has one of the most complete listings of company licensing information of any of the drug pipeline directories. Company data can include the company originally developing the drug, as well as companies that may subsequently license it.

    Learn More      Learn More
  3. Patent information is also available. File 445 usually includes one or two patent numbers for follow-up as well as complementing its coverage with notes on possible intellectual property issues. It also contains the patent assignee, which reflects original filing names (i.e., subsidiaries or names perhaps no longer used, due to subsequent mergers). In fact, this file has better pharmaceutical patent information than some of the patent files.
2/3/2 
DIALOG(R)File 445: IMS R&D Focus
(c) 2007 IMS Health & Affiliates. All rights reserved.

02014304 ** Image available ** 

Drug Name: vatalanib; vatalanib   
R&D Focus - January 22, 2007 (20070122 )
chemical structure
COMPANY INFORMATION:     Tip 2-4
Originator: Bayer Schering; (Germany); Bayer; co-developer; NA 
Licensee/Licensor: Novartis; (Switzerland); NA; co-developer; NA 
Patent Assignee: Novartis     Tip 2-5

Go to the next page to learn more about the Drug Information contained on the bibliographic record.


2-4

Authoritative Answers Enriched by ProQuest

Search Tip 2-3

Use Format 3 or MEDIUM to obtain the bibliographic citation for a record in File 445.

Examples:
type s1/3/1
type s1/medium/1

Learn More #2:

It is important to see what companies are involved with a drug. We want to know who is developing the drug and where the company is located.

IMS is the only pipeline directory that consistently identifies the Parent company name for subsidiaries cited in either its Originator or Licensee fields. At other stages in the development process, we might want to see who is licensing the drug. File 445 also has this information.

Dialog allows us to search for these specific pieces of information about companies.

/CO, CO=

Includes Company Name of Licensor/Originator, Licensee/Licensor. Display includes country of Licensee/Licensor, and Patent Assignee.

Example:
S CO=MERCK?

/LI, LI=

Licensee/Licensor. Display includes Licensee/Licensor Country, Parent Company of Licensee/Licensor, Company Relationship, and Originator, Region of Originator.

Example:
S TAKEDA/LI

/LO, LO=

Licensor/Originator. Display includes Company Name of Originator Country, Parent Company of Originator, Company Relationship, and Region of Originator.

Example:
S LO=ALMIRALL?

IP=

Parent Company. This field can be further qualified to Parent Company of Originator or Parent Company of Licensee.

Examples:
S IP=JOHNSON?
S IP =JOHNSON?/LO
S IP =JOHNSON?/LI

/PA, PA=

Includes Patent Assignee

Example:
S PA=MERCK?

Note 1: More than 80 countries in the developmental stage/status indexing segments of online records are listed. Locations for originators and licensees are consistently identified.

Note 2: You may also want to EXPAND to retrieve the exact spelling of the corporate name (e.g., expand pa=merck).

Print page

Learn More #3:

IMS R&D Focus tags records for each new product as "available" when the originating company announces its intention or willingness to seek joint marketing or research agreements. At the same time, contact information is added to records for quick follow-up.

Example:
s avail? (2n) (licens? or partner?)
s s1/avail
     <—(in Drug Profile records only)

File 445 consistently identifies parent companies for both originators and licensees, if they are subsidiaries. Both types of names are fully searchable. The parent company is indexed on the IP= field and is displayed as the second company name on the CO field as well as identified on the IP field. A sample search might look like this:

E co=[company name, e.g. centocor]
S e number(s)
S lo=[licensor's name, e.g. centocor]
S s2/profile and dp=preclinical

Print page

Search Tip 2-4

In the News records only, you can use CC= to retrieve the Licensee/Licensor Country. Use the suffixes (/LI or /LO) to restrict to Licensee or Licensor.

Examples:
S CC=JAPAN/LI
S CC=GERMANY/LO

Search Tip 2-5

Locate pharmaceutical patents by drug name, therapeutic area or patent expiration date.